Protective Effect of Yeast β-glucan on Immune System of Mice Irradiated by Carbon Ions
doi: 10.11804/NuclPhysRev.29.03.285
- Received Date: 1900-01-01
- Rev Recd Date: 1900-01-01
- Publish Date: 2012-09-20
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Key words:
- Yeast β-glucan /
- 12C6+ion /
- radiation protection
Abstract: To detect Yeast β-glucan’s protective effect on mice’s immune system after C ion beam radiation, mice were used as the test model. We observed the weight, hair color and behavior of mice everyday within a 7 d period of time after irradiation. Meanwhile, the content of white blood cell, on the 2nd and 7th day after irradiation was detected. We detected the thymus and spleen SOD, GSHPX activity and MDA content of the mice on the 8th day. The results showed that yeast βglucan could reduce the rapid weight loss of mice, increase white blood cell content, increase thymus and spleen SOD, GSHPX activity, decrease MDA content of thymus and spleen. These results indicate that yeast βglucan can protect mice’s immune system against C ion beam radiation damage.
Citation: | WANG Ying, LU Dong, WEI Wei, JING Xi-gang, WANG Ju-fang, LI Wen-jian. Protective Effect of Yeast β-glucan on Immune System of Mice Irradiated by Carbon Ions[J]. Nuclear Physics Review, 2012, 29(3): 285-289. doi: 10.11804/NuclPhysRev.29.03.285 |