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LIU Xin-guo, LI Qiang, #, DAI Zhong-ying. Method of Dose Calculation for Heavyion Cancer Therapy at IMP[J]. Nuclear Physics Review, 2009, 26(1): 69-75. DOI: 10.11804/NuclPhysRev.26.01.069
Citation: LIU Xin-guo, LI Qiang, #, DAI Zhong-ying. Method of Dose Calculation for Heavyion Cancer Therapy at IMP[J]. Nuclear Physics Review, 2009, 26(1): 69-75. DOI: 10.11804/NuclPhysRev.26.01.069
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Method of Dose Calculation for Heavyion Cancer Therapy at IMP

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  • Basic algorithms of biological effective dose optimization and dose distribution on CT image for the heavy ion therapy project at the Institute of Modern Physics (IMP)， Chinese Academy of Sciences (CAS) are reported in this paper. Firstly， biological effective dose optimization is conducted in water. According to the relationship between CT number and water equivalent path length， an integral algorithm is used to calculate the average dose within a pixel and then the dose distribution in tissue is derived. Secondly， the dose determination of layerstacking conformal irradiation is described and the layerstacking method is proposed to be applied in twodimensional conformal irradiation. These methods are sufficient to the requirements of the ongoing and future heavyion clinical trials conducted at IMP.
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