Theoretical Exploration on Ultra-fractionated Radiotherapy
doi: 10.11804/NuclPhysRev.23.02.242
- Received Date: 1900-01-01
- Rev Recd Date: 1900-01-01
- Publish Date: 2006-06-20
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Key words:
- hyper-radiosensitivity /
- ultra-fractionation /
- 50% tumor control rate
Abstract: Based on the survival data of human hepatoma SMMC-7721 and normal liver L02 cells irradiated with γ-rays at 0.3 Gy and 2 Gy, the possibility of uhra-fractionated radiotherapy is discussed in this paper. According to calculations, it is found that if the difference in cell survival between target tumor and adjacent normal tissue is up to 3%, radiotherapy using HRS would be realized through uhra-fractionation. Furthermore, the low-dose response is time-dependent. After analyzing this phenomenon, it was pointed that there would be a correlation between fractionation interval and the duration of cell G2 phase.
Citation: | JIN Xiao-dong, LI Qiang, GUO Chuan-ling, WANG Ju-fang, LI Wen-jian, YAN Zheng, DAI Zhong-ying, . Theoretical Exploration on Ultra-fractionated Radiotherapy[J]. Nuclear Physics Review, 2006, 23(2): 242-245. doi: 10.11804/NuclPhysRev.23.02.242 |