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新型融合BEV/BPV信息的高分辨率快速磁共振成像方法

A Novel High-resolution Fast Magnetic Resonance Imaging Method Incorporating BEV/BPV Fusion Information

  • 摘要: 建立了一种新型融合Beam Eye View(BEV)/Beam Path View(BPV)信息的高分辨率快速磁共振成像方法。选取3例肝转移磁共振引导放疗(MRgRT)患者,采集同一患者使用腹部加压带限制腹部运动(RAM组) 的运动管理模式下和自由呼吸(FB组)模式下图像,共计31 200帧。采用邻近肿瘤具有明确边界的血管进行肿瘤位置跟踪,计算其在95%置信区间下的径向矢量运动幅度差异△R95。在BEV/BPV平面上RAM组和FB组在所有分次中的△R95的差异分别为:患者1均小于0.58 mm;患者2高达2.57 mm以上;患者3分别为0.71 mm/1.05 mm。结果表明,腹部压迫方案可以有效地减小肿瘤的运动幅度,另外肿瘤运动幅度△R95变化具有完全的个体相关性。该方法也可作为MRgRT技术中肿瘤放疗外放边界缩小的影像基础。

     

    Abstract: This study establishes a novel high-resolution fast magnetic resonance imaging(MRI) method that incorporates Beam Eye View(BEV) and Beam Path View(BPV) fusion information. Three liver metastasis patients undergoing MRI guided radiotherapy(MRgRT) were selected. A total of 31 200 frames of MRI images were acquired from each patient using two motion patterns: restricted abdominal motion using an abdominal compression belt(RAM group) and free breathing(FB group). Tumor tracking was performed using nearby vessels with clear boundaries, and the radial vector motion amplitude difference(∆R95) within the 95% confidence interval was calculated. The differences in ΔR95 between the RAM and FB groups in all fractions on the BEV/BPV plane were as follows: for Patient 1, they were all less than 0.58 mm; for Patient 2, they were greater than 2.57 mm; for Patient 3, they were 0.71 and 1.05 mm, respectively. The results indicate that the abdominal compression technique can effectively reduce tumor motion magnitude, and the tumor motion magnitude ΔR95 variation is highly individual-specific. This method can serve as an imaging basis for the tumor margin reduction in MRgRT.

     

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