Abstract: The nuclear energy development accelerator mass spectrometer is an accelerator independently developed by China Institute of Atomic Energy. The device adopts a vacuum insulation and high-pressure injection method, overcoming the drawbacks of large volume, high construction cost, and high voltage safety hazards of atmospheric insulation mass spectrometers. At the same time, for the injection of 15 MPa stripping gas, a PID control circuit is used, with an accuracy of 0.1%. The ion source target control is driven by a servo motor and has a fine-tuning function, with a fine-tuning accuracy of 0.04^\circ. The control system has complete functions and adopts a 16 bit Siemens 1500 PLC architecture for high-precision measurement and control needs; At the same time, the safety interlock design has been strengthened, enhancing the safety and reliability of the device. The designed mass spectrometer has a compact structure, small land area occupied, and high control accuracy. After a long period of operation, it has been shown that the control system is stable and reliable, meeting the various functional requirements of the device.