Abstract: The accuracy and reliability of Th-U fuel cycle nuclear data have an important impact on the safety and economy of thorium based molten salt reactor. However, the existing nuclear data, which are developed based on U-Pu fuel cycle, will arise high uncertainty in the nuclear design of thorium molten salt reactor. In order to improve the applicability of nuclear data for the physical design of thorium molten salt reactor, a compact photoneutron source (PNS) driven by a 15 MeV electron LINAC was designed and built up by Shanghai Institute of Applied Physics of CAS for the measurement of Th-U fuel cycle nuclear data. The PNS has passed the technical acceptance, and carried out a series of nuclear data measurement for key nuclides, which are used for verifying the reliability of existing nuclear data and providing the basic experimental data for the evaluation and improvement of nuclear data.