放疗中二次原发性肿瘤的研究进展
Progress in Second Primary Cancer Research
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摘要: 回顾了辐射致癌方面的研究进展和二次原发性肿瘤在放射医学领域中的提出和发展， 总结了辐射致癌的一般特征以及主要医用放射性装置对二次原发性肿瘤发病的影响。重点阐述了年龄、 性别、 组织敏感性和照射剂量等重要影响因素在二次原发性肿瘤发病上造成的差异和原因。讨论了部分潜在的影响因素。展望了二次原发性肿瘤方面研究的前景和在放射治疗领域中的重要意义。
The progress in radiocarcinogenesis research and recent concerns about second primary cancer incidence after radiotherapy are reviewed. Several generalizations about radiation carcinogenesis and a brief look into medicaluse radiation sources are also summarized. The mostly confirmed dominant risk factors of second primary cancer are elucidated, some potential risk factors are proposed and discussed briefly. At the end of this review we presented our perspective on the future of second primary cancer research and its potential benefit.Abstract: The progress in radiocarcinogenesis research and recent concerns about second primary cancer incidence after radiotherapy are reviewed. Several generalizations about radiation carcinogenesis and a brief look into medicaluse radiation sources are also summarized. The mostly confirmed dominant risk factors of second primary cancer are elucidated, some potential risk factors are proposed and discussed briefly. At the end of this review we presented our perspective on the future of second primary cancer research and its potential benefit.
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