重离子照射细胞存活率计算的局部效应模型的缺陷

Disfigurement of ScholzKraft’s Local Effect Model for Calculation of Cell Survival After Heavyion Irradiation

摘要: 概略介绍了重离子照射细胞存活率计算的局部效应模型，讨论了该模型在理论假设和计算方法上存在的问题，指出了其中的任意参数，并通过计算检验了这些任意参数的取值变化对细胞存活率计算结果的影响。结果表明, 细胞存活率计算结果严重依赖于这些任意参数的取值。 ScholzKraft’s Local Effect Model (LEM) for the calculation of cell survival after heavyion irradiation was briefly introduced. Basing on the energy conservation law and the definition of the dose， the disfigurement of LEM in theoretical framework and methods was discussed. Two artificial parameters were found in LEM， and the result obtained from this model seriously depends on these two parameters.

Abstract: ScholzKraft’s Local Effect Model (LEM) for the calculation of cell survival after heavyion irradiation was briefly introduced. Basing on the energy conservation law and the definition of the dose， the disfigurement of LEM in theoretical framework and methods was discussed. Two artificial parameters were found in LEM， and the result obtained from this model seriously depends on these two parameters.