辐射诱导的DNA修复与细胞凋亡的ATP调控

Regulation of ATP on DNA Repair and Cell Apoptosis Induced by Irradiation

摘要: 综述了DNA辐射损伤导致的细胞阻遏于G1期以及在该时期对DNA的修复活动，提出了较大剂量辐射诱导的三磷酸腺苷不足导致细胞凋亡的假说，并分析了细胞走向凋亡与修复的辨正关系。
DNA damage induced by irradiation，which makes the cell arrested at G1 stage and DNA repair being activated in this stage，are summarized. It is proposed that the deficiency of adenosine triphosphate which is induced by the larger irradiation dose, induces cell apoptosis. And the relationship of cell selecting repair and apoptosis is also analyzed.

Abstract: DNA damage induced by irradiation，which makes the cell arrested at G1 stage and DNA repair being activated in this stage，are summarized. It is proposed that the deficiency of adenosine triphosphate which is induced by the larger irradiation dose, induces cell apoptosis. And the relationship of cell selecting repair and apoptosis is also analyzed.