Metabolic Effect of Streptomyces Avermitilis Irradiated by Ion Beam of 12C6+
doi: 10.11804/NuclPhysRev.30.02.195
- Received Date: 1900-01-01
- Rev Recd Date: 1900-01-01
- Publish Date: 2013-06-20
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Key words:
- pH value /
- concentration of mycelium /
- sugar content /
- nitrogen content /
- effect of metabolic
Abstract: pH value, mycelium concentration, carbon source and nitrogen metabolism in flask fermentation of the mutant high-producing strain ZJAV-Y1-203 and the original strain ZJAV-A1 have been investigated, in order to show the metabolic effect of avermitilis irradiated by ion beam of 12C6. In early stage (48 h) of the fermentation, pH value of the original fermentation was lower than that of the mutant strains. In 96~196 h of fermentation, the nitrogen utilization in the strains ZJAV-Y1-203 was higher than that in the original strains, its reproductive was fast, and its growing was vigorous. The mycelium concentration of ZJAV-Y1-203 was greater than the original strain, and the pH value of fermentation were stable, so its metabolism was relatively more stable. In 144240 h of fermentation, the strain ZJAV-Y1-203 on sugar consumption was less than the original strains. The effect of 12C6 ion irradiation on metabolism of Streptomyces avermitilis is conducive to the synthesis of avermectin.
Citation: | WANG Shuyang, BO Yongheng, WANG Lihua, CHE Jihong, LI Wenjian, LIANG Jianping, LIU Jing. Metabolic Effect of Streptomyces Avermitilis Irradiated by Ion Beam of 12C6+[J]. Nuclear Physics Review, 2013, 30(2): 195-200. doi: 10.11804/NuclPhysRev.30.02.195 |