Progress  in  Studies  on  Nucleolus  Functions

CHANG  Lei; ZHOU  Guang-ming; #

doi:10.11804/NuclPhysRev.28.01.126

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CHANG Lei, ZHOU Guang-ming, #. Progress in Studies on Nucleolus Functions[J]. Nuclear Physics Review, 2011, 28(1): 126-129. doi: 10.11804/NuclPhysRev.28.01.126

Citation:

CHANG Lei, ZHOU Guang-ming, #. Progress in Studies on Nucleolus Functions[J]. Nuclear Physics Review, 2011, 28(1): 126-129. doi: 10.11804/NuclPhysRev.28.01.126

Progress in Studies on Nucleolus Functions

doi: 10.11804/NuclPhysRev.28.01.126

1 Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China; 2 Graduate University of Chinece Academy of Sciences, Beijing 100049, China

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2011-03-20

Abstract

Nucleoli is the sites for ribosome synthesis and processing， however， recent approaches have revealed that it is also involved in variety of cellular processes， especially the cellular stress response. As sensors， nucleoli regulate the localization of nucleolar proteins， such as (Alternate Reading Frame， ARF)， and the activation of key factors， such as P53， and consequently mediate the cellular stress response. In this paper， recent progress in the studies on nucleolar functions in cellular stress response to radiation is reviewed.
- cellular stress,
- ionizing radiation,
- radiobiological effect,
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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Progress in Studies on Nucleolus Functions

doi: 10.11804/NuclPhysRev.28.01.126

1 Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China; 2 Graduate University of Chinece Academy of Sciences, Beijing 100049, China

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2011-03-20

Key words:

Abstract: Nucleoli is the sites for ribosome synthesis and processing， however， recent approaches have revealed that it is also involved in variety of cellular processes， especially the cellular stress response. As sensors， nucleoli regulate the localization of nucleolar proteins， such as (Alternate Reading Frame， ARF)， and the activation of key factors， such as P53， and consequently mediate the cellular stress response. In this paper， recent progress in the studies on nucleolar functions in cellular stress response to radiation is reviewed.

CHANG Lei, ZHOU Guang-ming, #. Progress in Studies on Nucleolus Functions[J]. Nuclear Physics Review, 2011, 28(1): 126-129. doi: 10.11804/NuclPhysRev.28.01.126

Citation:

CHANG Lei, ZHOU Guang-ming, #. Progress in Studies on Nucleolus Functions[J]. Nuclear Physics Review, 2011, 28(1): 126-129. doi: 10.11804/NuclPhysRev.28.01.126