不同LET   C离子束对粘红酵母菌的突变效应分析

孙海宁; 王菊芳; #; 马爽; 陆栋; 吴鑫; 李文建

doi:10.11804/NuclPhysRev.28.01.122

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不同LET C离子束对粘红酵母菌的突变效应分析

孙海宁, 王菊芳, #, 马爽, 陆栋, 吴鑫, 李文建

文章导航 > 原子核物理评论 > 2011 > 28(1): 122-125

孙海宁, 王菊芳, #, 马爽, 陆栋, 吴鑫, 李文建. 不同LET C离子束对粘红酵母菌的突变效应分析[J]. 原子核物理评论, 2011, 28(1): 122-125. doi: 10.11804/NuclPhysRev.28.01.122

引用本文:

SUN Hai-ning, WANG Ju-fang, #, MA Shuang, LU Dong, WU Xin, LI Wen-jian. Analysis of Mutagenic Effects Induced by Carbon Beams at Different LET in a Red Yeast Strain[J]. Nuclear Physics Review, 2011, 28(1): 122-125. doi: 10.11804/NuclPhysRev.28.01.122

Citation:

SUN Hai-ning, WANG Ju-fang, #, MA Shuang, LU Dong, WU Xin, LI Wen-jian. Analysis of Mutagenic Effects Induced by Carbon Beams at Different LET in a Red Yeast Strain[J]. Nuclear Physics Review, 2011, 28(1): 122-125. doi: 10.11804/NuclPhysRev.28.01.122

不同LET C离子束对粘红酵母菌的突变效应分析

doi: 10.11804/NuclPhysRev.28.01.122

1 兰州大学药学院, 甘肃兰州 730000; 2 中国科学院近代物理研究所, 甘肃兰州 730000

Analysis of Mutagenic Effects Induced by Carbon Beams at Different LET in a Red Yeast Strain

(1 School of Pharmacy, Lanzhou University, Lanzhou 730000, China; 2 Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China

摘要: 以粘红酵母菌Rhodotorula glutinis AY 91015为材料，研究了不同传能线密度（LET）的C离子对粘红酵母菌的失活截面和突变截面，评估了不同LET的C离子对微生物的失活效应和突变效应。结果表明， C离子LET为120.0 keV/μm时，单个粒子对粘红酵母菌的失活截面最大，为4.37 μm2，接近酵母菌细胞核的平均核截面； LET为96.0 keV/μm时，单个粒子对粘红酵母菌的突变截面最大。通过对C离子束致突变能力的分析发现， C离子在LET为58.2 keV/μm时突变能力最强，这一结果显示在经C离子辐照后存活下来的粘红酵母菌中，可以引起有效突变的最佳LET为58.2 keV/μm左右，此时所对应的碳离子能量约为35 MeV/u。这些结果表明， C离子对粘红酵母菌的最佳致死效应和最佳致突变效应存在于不同的能量区域。 To evaluate inactive and mutagenic effects of carbon beam at different LET， the inactivation cross section and mutation cross section induced by carbon beams of different LET values were investigated in a red yeast strain Rhodotorula glutinis AY 91015. It was found that the maximum inactivation cross section of 4.37μm2 , which was very close to the average nucleus cross section, was at LET of 120.0 keV/μm. The maximum mutation cross section was at LET of 96.0 keV/μm. Meanwhile， the highest mutagenicity of carbon ion was found around 58.2 keV/μm. It implied that the most efficient LET to induce mutation in survival yeasts was 58.2 keV/μm， which corresponded to energy of 35 MeV/u carbon beam. The most effective carbon beam to induce inactivation and mutation located at different energy region.
- C离子 /
- 传能线密度 /
- 失活效应 /
- 突变效应 /
- 粘红酵母菌
Abstract: To evaluate inactive and mutagenic effects of carbon beam at different LET， the inactivation cross section and mutation cross section induced by carbon beams of different LET values were investigated in a red yeast strain Rhodotorula glutinis AY 91015. It was found that the maximum inactivation cross section of 4.37μm2 , which was very close to the average nucleus cross section, was at LET of 120.0 keV/μm. The maximum mutation cross section was at LET of 96.0 keV/μm. Meanwhile， the highest mutagenicity of carbon ion was found around 58.2 keV/μm. It implied that the most efficient LET to induce mutation in survival yeasts was 58.2 keV/μm， which corresponded to energy of 35 MeV/u carbon beam. The most effective carbon beam to induce inactivation and mutation located at different energy region.
- carbon beam /
- linear energy transfer /
- inactive effect /
- mutagenic effect /
- red yeast

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不同LET C离子束对粘红酵母菌的突变效应分析

doi: 10.11804/NuclPhysRev.28.01.122

1 兰州大学药学院, 甘肃兰州 730000; 2 中国科学院近代物理研究所, 甘肃兰州 730000

收稿日期: 1900-01-01
修回日期: 1900-01-01
刊出日期: 2011-03-20

关键词:

C离子 /

摘要: 以粘红酵母菌Rhodotorula glutinis AY 91015为材料，研究了不同传能线密度（LET）的C离子对粘红酵母菌的失活截面和突变截面，评估了不同LET的C离子对微生物的失活效应和突变效应。结果表明， C离子LET为120.0 keV/μm时，单个粒子对粘红酵母菌的失活截面最大，为4.37 μm2，接近酵母菌细胞核的平均核截面； LET为96.0 keV/μm时，单个粒子对粘红酵母菌的突变截面最大。通过对C离子束致突变能力的分析发现， C离子在LET为58.2 keV/μm时突变能力最强，这一结果显示在经C离子辐照后存活下来的粘红酵母菌中，可以引起有效突变的最佳LET为58.2 keV/μm左右，此时所对应的碳离子能量约为35 MeV/u。这些结果表明， C离子对粘红酵母菌的最佳致死效应和最佳致突变效应存在于不同的能量区域。 To evaluate inactive and mutagenic effects of carbon beam at different LET， the inactivation cross section and mutation cross section induced by carbon beams of different LET values were investigated in a red yeast strain Rhodotorula glutinis AY 91015. It was found that the maximum inactivation cross section of 4.37μm2 , which was very close to the average nucleus cross section, was at LET of 120.0 keV/μm. The maximum mutation cross section was at LET of 96.0 keV/μm. Meanwhile， the highest mutagenicity of carbon ion was found around 58.2 keV/μm. It implied that the most efficient LET to induce mutation in survival yeasts was 58.2 keV/μm， which corresponded to energy of 35 MeV/u carbon beam. The most effective carbon beam to induce inactivation and mutation located at different energy region.

English Abstract

Analysis of Mutagenic Effects Induced by Carbon Beams at Different LET in a Red Yeast Strain

(1 School of Pharmacy, Lanzhou University, Lanzhou 730000, China; 2 Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China

Received Date: 1900-01-01
Rev Recd Date: 1900-01-01
Publish Date: 2011-03-20

Keywords:

Abstract: To evaluate inactive and mutagenic effects of carbon beam at different LET， the inactivation cross section and mutation cross section induced by carbon beams of different LET values were investigated in a red yeast strain Rhodotorula glutinis AY 91015. It was found that the maximum inactivation cross section of 4.37μm2 , which was very close to the average nucleus cross section, was at LET of 120.0 keV/μm. The maximum mutation cross section was at LET of 96.0 keV/μm. Meanwhile， the highest mutagenicity of carbon ion was found around 58.2 keV/μm. It implied that the most efficient LET to induce mutation in survival yeasts was 58.2 keV/μm， which corresponded to energy of 35 MeV/u carbon beam. The most effective carbon beam to induce inactivation and mutation located at different energy region.

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