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丁楠, 周光明#. MicroRNA发现的研究现状及重离子辐照相关应用前景[J]. 原子核物理评论, 2009, 26(2): 172-176. DOI: 10.11804/NuclPhysRev.26.02.172
引用本文: 丁楠, 周光明#. MicroRNA发现的研究现状及重离子辐照相关应用前景[J]. 原子核物理评论, 2009, 26(2): 172-176. DOI: 10.11804/NuclPhysRev.26.02.172
DING Nan, ZHOU Guang-ming#. Progress on Finding Novel MicroRNAs and Expectation of Heavy Ion Irradiation Application in This Field[J]. Nuclear Physics Review, 2009, 26(2): 172-176. DOI: 10.11804/NuclPhysRev.26.02.172
Citation: DING Nan, ZHOU Guang-ming#. Progress on Finding Novel MicroRNAs and Expectation of Heavy Ion Irradiation Application in This Field[J]. Nuclear Physics Review, 2009, 26(2): 172-176. DOI: 10.11804/NuclPhysRev.26.02.172

MicroRNA发现的研究现状及重离子辐照相关应用前景

Progress on Finding Novel MicroRNAs and Expectation of Heavy Ion Irradiation Application in This Field

  • 摘要: MicroRNA(miRNA)是一类大小为19—24个核苷酸的非编码RNA, 它们通过与靶基因的信使RNA(mRNA)结合在转录后水平调节靶基因的表达, 因而在广泛的生物学过程中发挥重要作用。 首先从miRNA的获得和鉴定两方面对目前miRNA发现工作进行了概括, 然后分析和总结了近年来人源miRNA发现工作的现状, 最后提出有关新miRNA发现工作的新想法。 MicroRNAs(miRNAs) are one kind of small noncoding RNAs of 19—24 nucleotides that transcriptionally regulate the expression of target genes by binding to their mRNA and thus play a central role in gene regulation in a wide arrange of biological processes. In this paper, we reviewed the clone and identification of novel miRNAs, summarized recent work on novel human miRNA recognization, and proposed a potentially feasible way to discover more human miRNAs.

     

    Abstract: MicroRNAs(miRNAs) are one kind of small noncoding RNAs of 19—24 nucleotides that transcriptionally regulate the expression of target genes by binding to their mRNA and thus play a central role in gene regulation in a wide arrange of biological processes. In this paper, we reviewed the clone and identification of novel miRNAs, summarized recent work on novel human miRNA recognization, and proposed a potentially feasible way to discover more human miRNAs.

     

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