辐射诱导的DNA修复与细胞凋亡的ATP调控

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辐射诱导的DNA修复与细胞凋亡的ATP调控

周清明, 张红, #, 党秉荣, 李文建, 刘兵, 闵凤玲, 段昕, 谢漪

文章导航 > 原子核物理评论 > 2005 > 22(2): 225-228

周清明, 张红, #, 党秉荣, 李文建, 刘兵, 闵凤玲, 段昕, 谢漪. 辐射诱导的DNA修复与细胞凋亡的ATP调控[J]. 原子核物理评论, 2005, 22(2): 225-228. doi: 10.11804/NuclPhysRev.22.02.225

引用本文:

周清明, 张红, #, 党秉荣, 李文建, 刘兵, 闵凤玲, 段昕, 谢漪. 辐射诱导的DNA修复与细胞凋亡的ATP调控[J]. 原子核物理评论, 2005, 22(2): 225-228. doi: 10.11804/NuclPhysRev.22.02.225

ZHOU Qing-ming, ZHANG Hong, #, DANG Bing-rong, LI Wen-jian, LIU Bing, MIN Feng-ling, DUAN Xin, XIE Yi. Regulation of ATP on DNA Repair and Cell Apoptosis Induced by Irradiation[J]. Nuclear Physics Review, 2005, 22(2): 225-228. doi: 10.11804/NuclPhysRev.22.02.225

Citation:

ZHOU Qing-ming, ZHANG Hong, #, DANG Bing-rong, LI Wen-jian, LIU Bing, MIN Feng-ling, DUAN Xin, XIE Yi. Regulation of ATP on DNA Repair and Cell Apoptosis Induced by Irradiation[J]. Nuclear Physics Review, 2005, 22(2): 225-228. doi: 10.11804/NuclPhysRev.22.02.225

辐射诱导的DNA修复与细胞凋亡的ATP调控

doi: 10.11804/NuclPhysRev.22.02.225

1 中国科学院近代物理研究所, 甘肃兰州 730000; 2 中国科学院研究生院, 北京 100039

Regulation of ATP on DNA Repair and Cell Apoptosis Induced by Irradiation

1 Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China; 2 Graduate School of Chinese Academy of Sciences, Beijing 100039, China

摘要: 综述了DNA辐射损伤导致的细胞阻遏于G1期以及在该时期对DNA的修复活动，提出了较大剂量辐射诱导的三磷酸腺苷不足导致细胞凋亡的假说，并分析了细胞走向凋亡与修复的辨正关系。
DNA damage induced by irradiation，which makes the cell arrested at G1 stage and DNA repair being activated in this stage，are summarized. It is proposed that the deficiency of adenosine triphosphate which is induced by the larger irradiation dose, induces cell apoptosis. And the relationship of cell selecting repair and apoptosis is also analyzed.
- p53 /
- 辐射 /
- 三磷酸腺苷 /
- 凋亡
Abstract: DNA damage induced by irradiation，which makes the cell arrested at G1 stage and DNA repair being activated in this stage，are summarized. It is proposed that the deficiency of adenosine triphosphate which is induced by the larger irradiation dose, induces cell apoptosis. And the relationship of cell selecting repair and apoptosis is also analyzed.
- p53 /
- irradiation /
- adenosine triphosphate /
- apoptosis

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辐射诱导的DNA修复与细胞凋亡的ATP调控

doi: 10.11804/NuclPhysRev.22.02.225

1 中国科学院近代物理研究所, 甘肃兰州 730000; 2 中国科学院研究生院, 北京 100039

收稿日期: 1900-01-01
修回日期: 1900-01-01
刊出日期: 2005-06-20

关键词:

p53 /

三磷酸腺苷 /

摘要: 综述了DNA辐射损伤导致的细胞阻遏于G1期以及在该时期对DNA的修复活动，提出了较大剂量辐射诱导的三磷酸腺苷不足导致细胞凋亡的假说，并分析了细胞走向凋亡与修复的辨正关系。
DNA damage induced by irradiation，which makes the cell arrested at G1 stage and DNA repair being activated in this stage，are summarized. It is proposed that the deficiency of adenosine triphosphate which is induced by the larger irradiation dose, induces cell apoptosis. And the relationship of cell selecting repair and apoptosis is also analyzed.

English Abstract

周清明, 张红, #, 党秉荣, 李文建, 刘兵, 闵凤玲, 段昕, 谢漪. 辐射诱导的DNA修复与细胞凋亡的ATP调控[J]. 原子核物理评论, 2005, 22(2): 225-228. doi: 10.11804/NuclPhysRev.22.02.225

引用本文:

周清明, 张红, #, 党秉荣, 李文建, 刘兵, 闵凤玲, 段昕, 谢漪. 辐射诱导的DNA修复与细胞凋亡的ATP调控[J]. 原子核物理评论, 2005, 22(2): 225-228. doi: 10.11804/NuclPhysRev.22.02.225

ZHOU Qing-ming, ZHANG Hong, #, DANG Bing-rong, LI Wen-jian, LIU Bing, MIN Feng-ling, DUAN Xin, XIE Yi. Regulation of ATP on DNA Repair and Cell Apoptosis Induced by Irradiation[J]. Nuclear Physics Review, 2005, 22(2): 225-228. doi: 10.11804/NuclPhysRev.22.02.225

Citation:

ZHOU Qing-ming, ZHANG Hong, #, DANG Bing-rong, LI Wen-jian, LIU Bing, MIN Feng-ling, DUAN Xin, XIE Yi. Regulation of ATP on DNA Repair and Cell Apoptosis Induced by Irradiation[J]. Nuclear Physics Review, 2005, 22(2): 225-228. doi: 10.11804/NuclPhysRev.22.02.225

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